Guide to Purchasing Sequencing: 7th Version
The Latest Sequencing Buyer's Guide: Navigating the DNA Sequencing Landscape
The 7th Edition of the Sequencing Buyer's Guide, published on January 31, 2025, offers a comprehensive overview of the current DNA sequencing landscape. This guide, a valuable resource for buyers seeking to understand the rapidly evolving DNA sequencing market, covers various DNA sequencing technologies and platforms.
The guide begins with Chapter 1 - FIRST STEPS IN SAMPLE PREPARATION: NUCLEIC ACID EXTRACTION, setting the stage for the sequencing process. It delves into the challenges and ethical hurdles of using clinical data in genomic medicine, using newborn screening as an example, in Chapter 8.
Chapter 4 introduces the current commercial long-read sequencing methods, while Chapter 5 outlines how to choose the best sequencing technology for an experiment, considering factors such as sample type and research goals.
The guide provides detailed profiles of major sequencing instruments and their capabilities, including the Illumina NextSeq series and NovaSeq. It also highlights emerging trends such as AI-enhanced and portable sequencing devices.
Chapter 6 spotlights key single-cell, spatial, and multi-omics sequencing technologies. The guide offers up-to-date specifications of sequencing instrumentation and reagents used for NGS, displayed side by side for comparison.
Chapter 3 - MEET THE SHORT-READ SEQUENCERS provides an overview of short-read sequencing technologies. The guide also discusses the options for outsourcing sequencing experiments to external groups, departments, or companies.
Expert insights are a key feature of this edition, with interviews and panel discussions featuring professionals from academic, pharmaceutical, and clinical sectors. Notable contributors include Pankaj Agrawal, Rosie Bamford, Jack Bartram, and many more.
The guide concludes by addressing the ethical and logistical challenges of bringing sequencing to the clinic. It also provides information on Roche's new sequencing by expansion technology.
This edition of the Sequencing Buyer's Guide serves as a comprehensive resource for those navigating the complex world of DNA sequencing, offering practical advice and insights into the latest technologies and trends.
[1] Source: The Sequencing Buyer's Guide, 7th Edition, 2025. [3] Source: The Sequencing Buyer's Guide, 7th Edition, 2025.
- The 7th Edition of the Sequencing Buyer's Guide, published in 2025, outlines the ethical hurdles of using clinical data in genomic medicine, particularly in newborn screening.
- Chapter 1 of the guide focuses on the initial steps in sample preparation, specifically the extraction of nucleic acids.
- The guide discusses the current commercial long-read sequencing methods in Chapter 4 and presents advice on choosing the best sequencing technology for an experiment in Chapter 5, considering factors like sample type and research goals.
- Detailed profiles of major sequencing instruments like the Illumina NextSeq series and NovaSeq are provided in the guide, alongside highlights of emerging trends such as AI-enhanced and portable sequencing devices.
- Single-cell, spatial, and multi-omics sequencing technologies receive spotlight in Chapter 6 of the guide.
- Short-read sequencing technologies and the options for outsourcing sequencing experiments to external groups or companies are covered in Chapter 3, titled 'Meet the Short-Read Sequencers'.
